![]() ![]() The first people to speculate that it might be due to chromosomal abnormalities were Waardenburg and Bleyer in the 1930s. In the first part of the twentieth century, there was much speculation of the cause of Down syndrome. Instead, the condition became called "Down's syndrome." In the 1970s, an American revision of scientific terms changed it simply to "Down syndrome," while it still is called "Down's" in the UK and some places in Europe. This ethnic insult came under fire in the early 1960s from Asian genetic researchers, and the term was dropped from scientific use. Down was superintendent of an asylum for children with mental retardation in Surrey, England when he made the first distinction between children who were cretins (later to be found to have hypothyroidism) and what he referred to as "Mongoloids."ĭown based this unfortunate name on his notion that these children looked like people from Mongolia, who were thought then to have an arrested development. ![]() The formal story began in 1866, when a physician named John Langdon Down published an essay in England in which he described a set of children with common features who were distinct from other children with mental retardation. Trisomy 21: The Origin of Down Syndrome Last Updated:Ĭopyright 1997, 2000, 2003. ![]()
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